Title: To study the prevalence of mild cognitive impairment (MCI) and its subtypes in elderly person ≥ 60 years of age and to study the epidemiological aspect of MCI.
Methods: It is a randomized urban population based study conducted in northwest part of India, Bikaner city. Kolkata cognitive test battery (based on consortium to establish a registry for Alzheimer's disease and Hindi mental state examination, HMSE) was used to evaluate 270 apparently non-demented subjects. CDR scale and GDS scale were used to exclude severe cognitive impairment and dementia respectively.
Results: The total prevalence of MCI was 19.26%, the prevalence of a MCI and multiple domains MCI was 7.78% and 11.48% respectively. The age group wise, sex wise and education group wise break up of prevalence rates of MCI types were not significant. People with memory complaint had a MCI and multiple domain MCI prevalence (20.45%) and (25%) respectively. In people without memory complaints prevalence of a MCI and multiple domains MCI were (5.31%) (9.37%). Prevalence of a MCI and multiple domain MCI in hypertensive elderly were (9.1%) and (14.05%) and the same thing in non-hypertensive were (6.71%) and (9.48%). Prevalence of aMCI in diabetic and non-diabetic elderly were (16.98%) and (5.52%). Multiple domains MCI was found among (20.75%) diabetics and (9.21%) non-diabetic. Mean scores, 10th and 90th percentile values of a MCI cases and multiple domains MCI cases in all cognitive domains were low and statistically significant when compared to normal control elderly.
Conclusion: Advancing age, low education level, hypertension, diabetes mellitus, chronic smoking, low socio–economic status were associated with higher prevalence of MCI in elderly. There was no significant difference in prevalence rates of MCI between sexes in our study.