Study of Thyroid and Lipid Profile in Chronic Kidney Disease
Dr. B. Lakshmi Keerthana, Dr. T Anil Kumar
CKD encompasses a spectrum of different pathophysiology processes associated with abnormal kidney function, and a progressive decline in GFR. CKD affects thyroid function in many ways and is often associated with altered lipid metabolism. Hence, the present study was done to the present study was done in undialyzed CKD patients to determine serum Total T3, T4, TSH and serum lipid profile and compare them with healthy controls. The study group consisted of 130 subjects. Of these - 40 belong to stage 3 CKD (Group 2), 30 belong to stage 4 & 5 CKD (Group 3) and 50 were age and sex matched controls (Group 1). Results show that serum total T3, T4 and HDL were decreased while TSH and other lipid profile parameters were increased in CKD patients, when compared to control group. Hence CKD is associated with thyroid dysfunction and dyslipidemia.