Lethal effects ofrnMercury as insecticide on Zn status, Thyroid production and Lung capacities ofrnHuman body
Mercury is arnnaturally occurring element that is found in air, water and soil. Exposure tornmercury – even small amounts – may cause serious health problems, and is arnthreat to the development of the child in utero and early in life.rnMercury may have toxic effects on the nervous, digestive and immune systems,rnand on lungs, kidneys, skin and eyes. Mercury is considered by WHO as one ofrnthe top ten chemicals or groups of chemicals of major public health concern.rnMercury is well absorbed through the lungs, the gastrointestinal tract, and thernskin. Methyl mercury compounds vaporize easily and if inhaled in large amounts,rncan destroy lung tissue. The most common sensory effects of mercury toxicityrnare paresthesia, or a tingling sensation, pain in limbs, and visual andrnauditory disturbances. Motor disturbances are exhibited by changes in gait,rnweakness, falling, slurred speech, and tremors. Other symptoms are headaches,rnrashes and various emotional disturbances. We observed that suddenly somernswimmers they had severe hair loss and they felt abnormally extremernparasthenia, we came to know that some mercury based algalicide was added andrnthe results may be because of this. Discontinuation of swimming bring backrnnormal to the affected children, but it took many months. Based on this findingrnwe studied the effect of Parad Vati, a mercury containing tablet added to grainsrnand cereal sin common practice in India (Made by Sacrom Pharma Pvt Ltd, CaodernNo- 03, Product mane- Parazzest). We found that that as micro-organisationrninfection convert mercury in to methyl mercury compound that is not only morerntoxic but also more potentially absorbed in human body. As children and agedrnpersons are the vulnerable persons of any family, so we made two groups ofrnchildren and aged persons of the Parad Vati user family and also from thernnon-user family. So estimate their serum Zn level –Akita Abba method wasrnadopted, Lung Capacities was estimated in District hospital Bilaspur byrnSpirometry, Visual symptoms as abbesses in legs, rashes, twingling, and vertigornalso studied. The Status of Thyroid gland was estimated by T3, T4rnand TSH levels in both the groups. We found a significant differences in lungrncapacities of both the group- the user group showed an Asthma like spirometryrnpicture with reduced lung capacities, also their serum has body samples hasrnlower level of Zn, although this is insignificantly defferent. The T3, T4rnlevels were lower is Parad Vati users, TSH level was high in comparisonrnto non-users. (T3 -3.5 - 6.5 pmol/L, T4 10 - 23 pmol/L, TSH-0.5 - 4.70 mIU/L,rnSerum Zn -89µmol /l. This study suggests the possibility ofrnmercury toxicity by using Parad Vati in the studied subjects especially in agedrnpersons and children below 8 years of age.