International Journal of Medical and Health Research

International Journal of Medical and Health Research


International Journal of Medical and Health Research
International Journal of Medical and Health Research
Vol. 2, Issue 7 (2016)

Original research article: Study of efficacy of lignocaine given intravenously as a suppressant of post extubation laryngospasm and cough in children undergoing cleft lip and cleft palate surgeries


Dr. Priyanka Saini, Dr. Chand Kiran Yadav, Dr. Manish Khandelwal

Background: Lignocaine is amide type local anaesthetic with antiarrhythmic properties, produces electrical stabilization of cell membrane by blocking the sodium conductance.

Aims & Objectives: The aim of our study was to evaluate the effect of intravenous lignocaine in prevention of post extubation laryngospasm and coughing in children undergoing cleft lip and cleft palate surgeries.

Methodology: Eighty ASA grade I and II patients between three months to nine year age posted for cleft lip and cleft palate repair surgery, were randomly allocated to 2 groups, 40 patients in each group. Group A (n= 40) received lignocaine1.5 mg/kg intravenously and group B (n= 40) received normal saline 0.075 ml/kg intravenously 2 minute before extubation. Hemodynamic parameters (Heart rate, Blood pressure), oxygen saturation and severity of laryngospasm and coughing were observed for ten minutes following extubation.

Results: There was statistically significant reduction in the incidence of laryngospasm and coughing in lignocaine pretreated group.

Conclusion: Intravenous lignocaine is very effective drug in the prevention of post extubation laryngospasm and coughing in children undergoing cleft lip and cleft palate surgery.
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