Vol. 2, Issue 8 (2016)
The impact of gender on serum uric acid levels in hypertensive patients with left ventricular hypertrophy in Erbil city-Iraq
Author(s): Salam Naser Zangana
Abstract: Background and objectives: Serum uric acid (UA) level is frequently elevated in hypertension and its level tends to vary with gender. The objective of this study was to evaluate the impact of gender on serum uric acid levels in hypertensive patients with left ventricular hypertrophy (LVH) in Erbil-Iraq. Patients and methods: A total of 130 consecutive adult patients presenting with essential hypertension were included. They were classified into two groups; Group I (patients with LVH) and Group II (patients with non- LVH). The effects of gender on serum uric acid level were evaluated in both groups. Results: High UA level was present in 29 patients (22.3%), 17 of them (58.6%) were males. Serum UA level was significantly higher in male and female patients with LVH compared to those in non-LVH patients. The means of serum UA, interventricular septum, posterior wall, and left ventricular mass were significantly higher in male patients with LVH compared to those in female patients with LVH. Conclusions: High UA level was more common in male hypertensive patients than females and despite it was positively associated with Left ventricular (LV) mass and abnormal LV geometry in both genders; but its effect was greater in males than in females.