International Journal of Medical and Health Research

International Journal of Medical and Health Research


International Journal of Medical and Health Research
International Journal of Medical and Health Research
Vol. 2, Issue 8 (2016)

Assessment of the benefits of bispectral index monitoring for using volatile anaesthetic agents for anaesthesia


Dr. Pooja Patwa, Dr. Kalpana Desai, Dr. Pragna Vachhrajani, Dr. Pratiti Gohil

AIM: This study was done to compare the cost-effectiveness and utilization of volatile anaesthetic drugs, to ascertain the depth and adequacy of anaesthesia by using bispectral index monitoring in patients in general anaesthesia. Material and Methods: In this prospective randomized controlled study, 64 patients of either sex between age group of 18-64 years (ASA I and II) were allocated into four groups. Group 1:O2+N2O+Isoflurane+inj vecuronium 0.1 mg/kg+IPPV without BIS monitoring. Group 2:O2 +N2O+Isoflurane+inj vecuronium 0.1mg/kg+IPPV with BIS monitoring Group 3:O2+N2O+Sevoflurane+inj vecuronium 0.1mg/kg+IPPV without BIS monitoring Group 4:O2+N2O+Sevoflurane+inj vecuronium 0.1mg/kg+IPPV with BIS monitoring General anaesthesia was administered by usual method and maintained on O2+N2O+isoflurane/sevoflurane. All patients were monitored vitally every 10 mints interval. BIS monitoring is done in group 2&4 and BIS value was kept between 40-60. Requirement of inhalational agents and recovery time were calculated. Post-operative vital data, sedation scale and side effects were recorded. Results: Recovery of patient was faster in BIS titrated group (Group II&IV) as compared to control group (Group I&III) (P<0.05).Total volume of volatile anaesthetic agent Isoflurane and sevoflurane used was significantly lower in BIS titrated group than control group (P<0.001). In BIS guided anaesthesia patient remained hemodynamically stable throughout surgery. Conclusion: Titrating isoflurane and sevoflurane using BIS monitor decreased their utilization and contributed to a faster emergence from anaesthesia.
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