Vol. 3, Issue 10 (2017)
Study of histomorphological spectrum of ovarian tumours
Author(s): Dr. Neha Garg, Dr. AS Anand, Dr. Chaya Annigeri
Abstract: Background: Ovarian tumours are a heterogeneous neoplasms with a varied clinical, morphological and histological features. Objectives: To study the frequency, age distribution and the diverse histomorphological spectrum of ovarian tumours. Materials and Methods: This retrospective and prospective study of 3 years comprised of 85 ovarian tumours diagnosed in the Department of Pathology, Navodaya Medical College, Raichur. After thorough gross examination, representative bits were routinely processed and stained with H & E. Tumours were classified as per WHO classification. Special stains were done wherever required. Results: Out of 85 cases studied, majority were benign tumours (81.2%), followed by malignant (17.6%) and borderline tumour (1.2%). Age ranged from 11-70 years. Epithelial tumours were most common (70.6%), followed by germ cell tumours (18.8%), sex cord stromal tumours (8.2%) and metastatic ovarian tumours (2.4%). Serous cystadenoma was the commonest benign tumour and serous cyst adenocarcinoma was the commonest malignant ovarian tumour. Conclusion: The prognosis and varying therapeutic strategies of ovarian tumours necessitate an accurate pathological evaluation. Although newer techniques like IHC and molecular analysis have made the diagnosis easier and more precise, in the institutes with provision of limited resources, histopathological study is still the gold standard in diagnosing most of these tumours.