Vol. 3, Issue 11 (2017)
Gastrointestinal manifestations in type 2 diabetes mellitus
Author(s): Dr. Ajay Pal Singh, Dr. Yogita Gadariya
Abstract: Background: Gastrointestinal (GI) motor dysfunction in patients with diabetes affects esophagus, stomach and lower GI tract. Many diabetes patients have upper and lower GI symptoms. Reports have shownthat GI tract related complications are now recognized as important cause of morbidity in patients with type 2 diabetes (T2DM). Aims and objectives: To study GI manifestations with duration and severity of diabetes in T2DM patients. Materials and Methods: Hundred T2DM patients were studied between November 2013 to August 2015 in the Department of Medicine, GR Medical College and JA Group of Hospitals, Gwalior, Madhya Pradesh. Details history, clinical profile and laboratory measurements, ECG, USG abdomen was performed in all the patients. Endoscopy was performed in patients who gave the written consent. Patients were asked about symptoms related to GI manifestation and diabetes, family and past history of disease. Results: Mean age, height, weight and BMIwere 54.24±12.64 years, 159.57±8.59 cm, 60.87±11.53 kg and 23.79±3.50 kg/m2 respectively. Male (64%) outnumbered the female (36%). Most common HbA1c group was 7-9% (41%) and maximum have diabetes duration of <5 years. Maximum patients presented with GI symptoms (78%). Most common GI symptoms was constipation (22%) followed by acid peptic disease (15%). Fatty liver (21%) followed by hepatomegaly (20%) was the most common USG finding. In GI endoscopy, gastritis (13.63%) was the most common abnormality followed by esophagitis (9.09%). Conclusion: Significant number of GI manifestations is observed in T2DM patients especially with increasing duration of diabetes and HbA1c.