International Journal of Medical and Health Research

International Journal of Medical and Health Research


(MCI Approved Journal)

ISSN: 2454-9142

Vol. 3, Issue 11 (2017)

Original Research Article: Side effect profile of nifedipine for tocolysis in pregnancy

Author(s): Dr. Chhavi Raman Baid, Dr. Norman D Morris
Abstract: Objective: Our study was to evaluate the incidence and severity of the side effects of nifedipine, and the management of suspected preterm labour.
Methodology: All women in whom it was decided to start tocolysis were given capsule nifedipine orally by using the following regimen-30 mg stat followed by 10 mg three times a day for 48 hours. Blood pressure along with temperature, respiratory rate and pulse rate were taken half an hour after the administration of the initial dose of nifedipine and repeated again after half an hour. And observations were recorded by the investigators.
Results: Data was analyzed using SPSS (PC+) version 11.0. Associations between the variables and outcome were evaluated using different significant tests like Fisher exact test and Pearson co-relation.
Conclusions: Most common clinical presentation was abdominal pain. Primigravida was commonly seen in women with preterm labour. Palpitation was the most significant side effect. Majority of cases were satisfied by the using of nifedipine treatment as a tocolytic.
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