Neonatal gynecomastia is defined as “benign proliferation of glandular breast tissue”. It is considered to be a physiological variant seen in approximately 70% of infants in the first few months. Hyperprolactinemia & neonatal gynecomastia may be caused by several physiological, pathological and even pharmacological conditions.
There are multiple drugs that cause an increase in the concentrations of serum prolactin such as antipsychotics, opioids (morphine) and so many more. We report a rare case of neonatal gynecomastia complicated by morphine with no similar cases are reported in humans. We are hoping by this case report we increase the awareness of the possible role of medications in inducing neonatal gynecomastia among pediatricians and neonatologists.