Vol. 3, Issue 2 (2017)
Assessment of age and gender related changes on tear production
Author(s): Raj Kumar, Amita Pardesi
Abstract: Background: Tear production decreases with age and in several conditions. There are various tests available to measure tear secretion. The Schirmer’s test is widely use for this purpose and the tear film breakup time (BUT) test is currently in use to measure tear film stability. The present study was conducted to estimate the age and gender-related changes in the results of Schirmer’s and tear film BUT tests in study population. Materials & Methods: This study included 100 subjects of age ranged 20-60 years. All subjects underwent a complete ophthalmic examination. The Schirmer’s and the tear film BUT tests were performed in both eyes of each subject. Tear film BUT was undertaken after instilling one drop of fluorescein (2% strip Alcon-Co) into the lower fornix and subjects were instructed to blink several times for a few seconds. The modified Schirmer’s basal and reflex tear secretion test was performed after resting period for 20 min in both eyes using standard Whatman number 41 filter paper strip, 5 mm wide and 35 mm long. Wetting was measured in millimeters after 5 minutes. Thus by doing this, both the reflex and basal tear production was calculated. Results: Out of 100 subjects, males were 50 and females were 50. The difference was non - significant (P – 1). The mean age of males was 42± 20.2 years and mean age of females was 41± 22.4 years. The mean schirmer test value in right and left eyes of males was 18.37 seconds and 21.01 seconds respectively. The mean schirmer test value in right and left eyes of females was 20.71 seconds and 19.55 seconds respectively. The difference was non - significant (P > 0.05). The mean tear film break- up time (TBUT) in right and left eyes of males was 18.99 seconds and 18.12 seconds respectively. The mean tear film break- up time (TBUT) in right and left eyes of females was 17.34 seconds and 17.86 seconds respectively. The difference was non - significant (P > 0.05). There was significant decrease in both TBUT and Schirmer’s test values with increasing age in both genders. Conclusion: There was variation in tear production in left and right eyes of both genders. There was significant decrease in tear production and tear film break up time in both males and females.
Please use another browser.