Vol. 3, Issue 2 (2017)
Clinicopathological study of encephalitis in greater Gwalior region: A hospital based study
Author(s): Dr. Atul Kumar Pandey, Dr. Raj Laxmi Sharma, Dr. Rajesh Gaur
Abstract: Introduction: Encephalitis is inflammation of the brain parenchyma. Viral infection is the most common cause of the condition. Aims And Objectives: To find out prevalence and encephalitis cases in hospital admitted patient at J.A Hospital, clinical spectrum of disease, laboratory parameter of routine CSF and Hematology and specialized molecular test. Material and Methods:Prospective study to find the prevalence of encephalitis in the greater Gwalior region of patients admitted in Neurology and Paediatric ward, conducted by Department of pathology G.R.M.C in association with D.R.D.E, patients samples of CSF, blood and serum will be used for routine and molecular diagnosis. Results and Observations: This evaluation and comparison of new molecular techniques RTPCR and Nucleotide Sequencing indicate that these test are highly specific in identifying etiological agent in viral encephalitis and has great potential value for use in epidemic situation. These molecular techniques can prove as a big asset to the society as they facilitate the early diagnosis of viral encephalitis and reduces the mortality and morbidity. Conclusion: Incidence of viral encephalitis is very less (04%) in this region, clear male preponderance in overall encephalitis cases (M:F = 1.6:1). Pediatric age group is the most affected group of encephalitis patients (0-10 yrs), rise in the incidence of west nile virus encephalitis in this region which was rare for this region.
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