Vol. 3, Issue 2 (2017)
A study on the association of serum vitamin D and iron level with level of control of childhood asthma
Author(s): Dr. Arvind Kumar Choudhary, Dr. Seema Choudhary, Dr. Gaurav Pandey, Dr. Supriya Sharma, Dr. Sushma Pandey
Abstract: Introduction: Associations between an unhealthy diet and asthma are reported. A recent attention has focused on the possible relationship between vitamin D and iron and the presence of asthma. The aim: To assess the levels of serum Vitamin-D and iron in children complaining of asthma to demonstrate their possible effect on asthma and pulmonary function. Methods: A cross sectional, case control study was designed. It included sixty patients with partly controlled asthma and uncontrolled asthma according to GINA criteria, 2010. Thirty healthy age and sex matched are included as control. All children were subjected to full history and clinical examination. Serum vitamin D and iron were measured. Pulmonary function was done. Results: 33.3% and 25% of control and asthmatics patients have insufficient vitamin D levels (20-30 ng/ml). The frequency of asthmatics patients with iron deficiency is significantly higher than control (46.7% Vs 16.7%) (p= 0.004). In uncontrolled group, vitamin D was correlated positively with absolute eosinophilic count (p= 0.002 &r = 0.5) and negatively with FEV1 (p = 0.01&r = - 0.5). Conclusion: High prevalence of vitamin D insufficiency in both asthmatic and healthy children. Vitamin D may play a role in asthma pathogenesis. Serum iron of asthmatics was lower than the healthy group. Recommendation Further prospective studies on large scale aiming the use of an inexpensive intervention in a substantial number of asthmatic children.
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