International Journal of Medical and Health Research

International Journal of Medical and Health Research


ISSN: 2454-9142

Vol. 3, Issue 2 (2017)

A study on effects of hepatitis b virus infection in children and adolescents

Author(s): Dr. Seema Choudhary, Dr. Arvind Kumar Choudhary, Dr. Gaurav Pandey, Dr. Supriya Sharma, Dr. Sushma Pandey
Abstract: Children tend to have higher alanine aminotransferase (ALT) levels early in life. The risk of hepatocellular carcinoma (HCC) is related to the duration of infection, the degree of histologic injury, and the replicative state of the virus (HBV DNA levels). The risk is higher in patients who are HBeAg-positive for extended periods or have basal core promoter mutants, and this risk is increased further in the presence of cirrhosis. Hepatocellular carcinoma in children with HBV infection has been described in both Asian4 and Western5 populations. Importantly, HCC has been described in children who had undergone early HBeAg seroconversion, indicating that there is still a risk for HCC even after viral replication decreases.
Pages: 119-122  |  968 Views  293 Downloads
publish book online
library subscription
Journals List Click Here Research Journals Research Journals
Please use another browser.