Vol. 3, Issue 4 (2017)
“Prevalence of Gastroesophageal reflux disease (GERD) in Bronchial asthma patients”
Author(s): Gayathri R, Elamurugan TP, Vishnu Kanth G, Sudharsanan S, Manwar Ali S
Abstract: Introduction: Gastroesophageal reflux disease (GERD) is one of the common gastro intestinal problem in surgical practice. Several studies have shown a close association between bronchial asthma and GERD. Data on prevalence of GERD in asthma patients in India are sparse. Aims and objective: To study the prevalence of Gastroesophageal reflux disease (GERD) in patients with bronchial asthma. Methodology: The study design was a case-control study. Adult bronchial asthma patients were included as cases. Age and gender matched controls were taken from non-asthmatic patients who attend pulmonary medicine OPD. GERD-Q questionnaire was used to assess the presence of GERD in both groups. GERD-Q score >8 was taken as presence of disease. Patients who had score >8 were subjected to upper GI endoscopy for documentation of GERD Results: A total of 80 bronchial asthma patients and 80 non-asthmatic controls were studied. On assessment for presence of reflux symptoms (heartburn and regurgitation) in both the groups, 52 patients (65%) in case and 29(36.5%) patients in control group had reflux symptoms. Heartburn was found to be the predominant reflux symptom in both the groups. 33 (41%) patients in the case group and 21 (26.25%) patients in control group had a total GERD-Q questionnaire score of more than 8. The difference in prevalence of GERD among the cases and controls were found to be statistically significant with a p value of 0.04, odds ratio of 1.9 (95% confidence limit - 1.008 - 3.878). Conclusion: Based on our study we conclude that there is increased prevalence of gastroesophageal reflux symptoms and gastroesophageal reflux disease in bronchial asthma patients. Heart burn is the predominant reflux symptom in bronchial asthma patients with reflux symptoms.
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