There had been a dramatic rise in the global incidence of dengue in the past few decades. Timely clinical intervention, etiological investigation, and disease control of the dengue infection is caused by the early diagnostic confirmation of dengue infection. Nowadays, market is flooded with a variety of rapid diagnostic tests (RDTs) and NSI antigen (Ag) targeting enzyme-linked immunosorbent assay [ELISA]. Hence; we undertook the present study to comparatively evaluate the efficacy of rapid SD (bioline) Dengue Duo test and ELISA for the detection of dengue infection.
Materials & Methods: The present study included assessment of records 160 patients who were suspected for dengue infection. In the central pathology laboratory of the intuition, blood samples of these were collected and were routinely processed for the identification of dengue infection. Testing with both SD Bioline Dengue Duo rapid test and ELISA was done after separating the serum from all the samples. All the results were recorded separately and analyzed and compared.
Results: Mean age of the patients of the present study was 28.5 years. Out of 160 patients, 110 were males while 50 were females. Out of 160 samples tested by rapid card test, 82 samples were found to be positive while 78 samples were found to be negative. Out of 82 samples tested by ELISA, positive results were obtained in 46 samples while negative results were obtained in 36 samples.
Conclusion: In addition to the identification of antibodies, Dengue rapid test also provides additional advantages of detecting NS1 antigens.