International Journal of Medical and Health Research

International Journal of Medical and Health Research


International Journal of Medical and Health Research
International Journal of Medical and Health Research
Vol. 3, Issue 6 (2017)

Pneumonia in Diabetics: Clinico-Bacteriological Profile and Outcome


Dr. Sayali Bhambar, Pranav Deore, Rahul Rathod, Smit Janrao

Introduction: The present study was thus planned to study and compare pneumonia in diabetics and non-diabetics with respect to clinical presentation, bacteriological profile, laboratory parameters, complications and prognosis.
Materials & Methods: A total of 50 consecutive diabetic subjects with confirmed pneumonia were included in the study after informed consent (Study Group- SG). A similar number of non-diabetic controls were also taken (Control Group – CG). Detailed clinical history, general examination and relevant investigations were carried out for all patients and noted down in a pre-designed pro-forma. Relevant investigations were carried out in all patients including sputum gram staining, Chest X-ray and sputum and blood culture. Patients were treated as per standard hospital protocol and were followed up after 2 weeks to assess symptomatic improvement and for repeating chest radiograph.
Results: The average age in SG was 57.93±9.71 yrs and in CG were 56.90±11.83 yrs (p-0.613). Most of the patients in both groups were males (78% in CG and 60% in SG; p-0.39). Multilobe involvement (> 2 zones involvement in chest x- ray) was more common in SG (40% in CG vs. 70% in SG) which is statistically significant (p<0.05). On Gram staining, Gram positive cocci were significantly more (p<0.05) in CG in comparison with SG (48% vs. 16%) while a combination of GPC/GNB was significantly more in SG than CG (30% vs. 6%). More number of mortalities were seen in diabetics (24%) in comparison with non-diabetics (10%). Patients in diabetic group were significantly more among PSI class IV and V (60% vs 34%) in comparison with non-diabetics, who were predominantly among PSI class I (P < 0.05).
Conclusion: In patients with pneumonia, Diabetes Mellitus is associated with polymicrobial etiology, multilobe involvement, increased ICU admissions, increased severity in the form of high PSI score and mortality.
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