A retrospective comparison of the effectiveness of ramosetron & ondansetron for the prevention of post-operative nausea
Dr. Shashi Bhushan Sinha
The Post-operative nausea and vomiting (PONV) is accountable for a conjoint obstacle of surgery and anaesthesia. Many of the patients have described that averting of PONV is of higher distress than escaping post-operative pain. PONV is also related with deferred release from the recovery room and persistent hospital care and, consequently it results in the increase in the health care expenditures. The study was conducted in the Hind Institute of Medical Sciences Mau, Ataria, sitapur. The age group of the patients is ranges from 25 to 65 years. Total 100 patients were evaluated for the study. As per the classification of the American Society of Anaesthesiologists I and II physical conditions were enrolled on to the study. Patients were randomly allocated to one of the following two groups to receive either injection ramosetron 0.3 mg IV or injection ondansetron 6 mg IV just before intubation. From the data obtained in the present study it can be concluded that ramosetron 0.3 mg is quite effective in controlling postoperative nausea and vomiting. It also lessens PONV score and occurrence of nausea in first 24 hours post operatively. We observed that the benefit was more in the later stages of the postoperative period.