Vol. 3, Issue 9 (2017)
Evaluation of gestational age as a risk factor for thrombocytopenia in preterm neonates
Author(s): Pardeep Goyal, Bhagwan S Natani, Ankit Agarwal, Sumit Bhatia, Malvika Kumar
Abstract: Background Thrombocytopenia is a common problem in preterm neonates. Thrombocytopenic neonates are at an increased risk of life threating complications. Hence this study was done with the objective to analyse gestational age as a risk factor associated with thrombocytopenia in preterm neonates. Methods This prospective study was conducted in Department of Paediatrics, National Institute of Medical Sciences & Research, Jaipur. All intramural, singleton preterm neonates were included in the study. Maternal ANC history, clinical feature, perinatal events and neonatal features were recorded in a proforma. Enrolled neonates were screened for platelet count between 12-24 hour of life and later at 72 hour of life. Platelet count was repeated daily in thrombocytopenic infant. Satistical analysis was done using software SPSS version 23. Results During the study period 5170 were born of which 183 were preterm babies. 168 preterm babies gave the consent for inclusion in the study. 56 (33.3%) neonates had thrombocytopenia. 35 (20.8%) neonates had early onset of thrombocytopenia and 21 (12.5%) had late onset. 24 (42.8%) had mild, 20 (35.7%) had moderate and 12 (21.4%) had severe thrombocytopenia. Gestational Age showed a significant association with thrombocytopenia in preterm neonates with moderated diagnostic accuracy.