Vol. 4, Issue 10 (2018)
Assessment of serum uric acid in patients suffered from essential hypertension
Author(s): Dr. Musarrat Parveen, Dr. Ram Binay Sinha
Abstract: Elevated serum uric acid level has been associated with increased risk for developing hypertension. The Normative Aging Study (NAS), a longitudinal study of aging begun in 1963 and with on-going follow-up, presented a unique opportunity to examine the relationship between serum uric acid level and the development of hypertension. The duration of follow-up, ≤40 years, allowed us to assess the durability of the prospective association of uric acid level with hypertension. Hence based on the above literature and findings the present study was planned to determine the prevalence and association of serum uric acid in patients diagnosed with essential hypertension. The current retrospective study was planned in Patna Medical College from Oct 2016 to Sept 2017 on total 80 patients were enrolled in the present study. The 40 patients were divided in the patients suffered from the essential hypertension and 40 patients were considered in the normal group as control cases. After overnight fasting, samples were collected in the morning. The samples were left standing for one hour and then serum was separated by centrifugation at 3000 rpm for 10 minutes. The samples were analysed on the same day on EM 360 fully auto analyser. Uric acid was measured using Uricase method. The data collected from the present study concluded that the Serum uric acid can be used as a biochemical marker to determine the severity and duration of hypertension. The relation in Serum uric acid levels between hypertensive patients and normotensive patients and Serum uric acid levels have direct relation to the duration and severity of hypertension.
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