Vol. 4, Issue 11 (2018)
Assessment of the prevalence of subclinical and overt hypothyroid disorders in pregnancy with respect to maternal and fetal outcome
Author(s): Dr. Sima Choudhary, Dr. Pratiksha Gupta
Abstract: The prevalence of Subclinical Hypothyroidism in South Asia especially in India is more than in other parts of the world and mostly due to autoimmune thyroiditis and nutrition deficiency. The gravity of the complications like abortion, preterm birth, weight gain, postpartum thyroiditis and converting to overt hypothyroidism in future, outweighs the cost of screening. Hence based on above literature findings the present study was planned to assess the occurrence of overt and subclinical thyroid dysfunction in pregnant women and its effect on the maternal and fetal outcomes. The 80 pregnant females referred for the treatment in the Department of the Gynaecology in ESI-PGIMSR, Basai Darapur were enrolled in the present study from Jan 2013 to Sept 2014. According to American Thyroid Association guidelines, normal TSH level is-0.1 to 2.5, 0.2 to 3, 0.3to3milli IU/L in first, second and 3rd trimesters respectively and these values were taken as reference for this study. In pregnancy, any value below these are hyperthyroidism and above are hypothyroidism. When T3, T4 values are normal and TSH is abnormal the disease is subclinical. Hence based on the above findings it is recommended for pregnant females to perform thyroid function test at the start of pregnancy. Hypothyroidism is a common disorder in women in their reproductive age. Untreated hypothyroidism can affect the pregnancy and the neonate in an adverse fashion; though hypothyroidism when adequately treated and monitored had good maternal and fetal outcome.