Vol. 4, Issue 12 (2018)
Assessment of lipid profile in patients suffered from hepatitis C viral disease
Author(s): Dr. Supriya Sharma, Dr. Gaurav Pandey
Abstract: The liver is the principal site for formation and clearance of lipoproteins. It receives fatty acids and cholesterol from peripheral tissues and diet, packages them into lipoprotein complexes, and releases these complexes back into the circulation. Thus, in severe liver disease, lipid metabolism is profoundly disturbed. Hepatitis C viral (HCV) disease has been linked with dyslipidemia. Based on above literature findings the present study was planned to assess the effect of HCV on lipid metabolism by observing the variations in serum lipoproteins (total cholesterol, low-density lipoprotein [LDL], high-density lipoprotein [HDL], very LDL [VLDL], and triglycerides [TGs]) in chronic hepatitis C viral patients. The study was conducted in the Career Institute of Medical Sciences And Hospital. We had conducted the study on about 60 patients admitted. The patients involved were suffering from HCV irrespective of their etiology. Hence from above findings it can be concluded that the advancement of Hepatitis C viral infection can lead to decrease level of lipid profile. Lipid profile monitoring may help in the diagnosis of hepatic infection severity and may also act as a good prognostic sign, so it must be analysed in all advanced hepatic infection cases.
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