International Journal of Medical and Health Research

International Journal of Medical and Health Research

(MCI Approved Journal)

ISSN: 2454-9142

Vol. 4, Issue 12 (2018)

A comparative study of ropivacaine alone versus ropivacaine with dexmedetomidine in supraclavicular brachial plexus block: A randomized double blind controlled study

Author(s): Dr. Zameeruddin, Dr. Mohammad Imranullah Khan
Abstract: Background and Aims: Supraclavicular brachial plexus block is frequently used procedure to provide anaesthesia and good post-operative analgesia for surgery on upper limb. The purpose of this study was to compare the, sedative and analgesic effects of ropivacaine alone versus ropivacaine given along with dexmedetomidine. Materials and Methodology: This prospective, randomized and double-blinded study included total 60 patients of either sex with age between 18-60 years posted for various elective upper limb surgery and randomly allocated into 2 equal groups of 30 each. Control Group-R received injection ropivacaine (0.75%) 30 ml plus 1 ml normal saline and Group-RD received injection ropivacaine (0.75%) 30 ml plus dexmedetomidine 25 μg (1 ml) for supraclavicular brachial plexus block using the peripheral nerve stimulator. Sensory and motor block evaluated with different time unsets. Results: There was no significant difference in the study groups with regards to demographic profile and duration of surgery. The onset of sensory and motor blockade was faster in Group-RD than Group-R. {Onset of sensory block: (Group-R=12.90±4.029 min and Group-RD=9.30± 5.861 min) (p<0.001), Onset of motor block: (Group-R=22.80±5.359 min and Group-RD=15.37±6.525 min) (p<0.001). Also total duration of sensory blockade {Group-R=393.70±88.318 mins, Group-RD=624.60±197.77 mins (p value<0.001)}, motor blockade {Group-R=339.40±78.16 mins, Group-RD=539.90±213.05 mins (p <0.000)}. All the results showed significant difference in both the groups. Conclusion: Dexmedetomidine in a dose of 25 μg added to ropivacaine in supraclavicular brachial block for upper limb surgery significantly shortens the onset time and prolongs the duration of sensory and motor block without producing sedation in patients.
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