Vol. 4, Issue 4 (2018)
Magnesium supplementation improve outcome after cardiac surgery
Author(s): Dr. Jyoti Prasad Kalita, Dr. Intekhab Alam, Manuj Kumar Saikia
Abstract: Hypomagnesaemia is common after cardiac surgery when done under cardiopulmonary bypass and it has association with increased morbidity and mortality. The purpose of this study was to determine whether magnesium supplementation in the immediate postoperative period improve outcome of post cardiac surgery patient. This retrospective observational study was conducted in a cardiac surgery intensive care unit of a tertiary care hospital. Seventy five patients undergoing elective cardiac surgery under cardiopulmonary bypass were to receive three doses of intravenous bolus of 1 g of magnesium sulphate at 8 hous interval in first 24 hours after surgery and another seventy five patient did not receive was taken as control group. There was signiﬁcant differences were found either in the primary end point (hours of intubation) or in the secondary end points (length of inotropic support, new atrial ﬁbrillation, ventricular tachycardia or ventricular ﬁbrillation, length of intensive care unit stay, or ICU or hospital mortality). Hypomagnesemia was present in 14% of patients on admission to the intensive care unit after operation. In conclusion, the magnesium supplementation after cardiac surgery with cardiopulmonary bypass does favorably affect clinical outcomes.
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