Vol. 4, Issue 5 (2018)
Organogenesis & histogenesis of kidney in human fetuses at different weeks of gestation
Author(s): Arpan Haldar, Dr. Manisha R Gaikwad, Soumya Chakraborty, Dipti Basu, Provas Banerjee
Abstract: Kidneys develop in early in 5th week and start to function around 9th week in the intermediate mesoderm of human embryos as metanephric kidney. Kidney is covered by a thick capsule made up of fibrous tissue beneath which cortico-medullary differentiation is well marked. Glomerulus with afferent & efferent arterioles are present in kidney. PCT, DCT, Collecting tubules & Duct of Bellini visible in medulla. Cortico-medullary junction well differentiated &Cortex is more than Medulla. Lobar & interlobar arteries seen in renal corpuscles. Lobulation & medullary rays visible in cortex. Between medullary rays multiple crescentic glomeruli visible. Bowman’s Capsule & subcapsular space present. These structures are absent in younger foetuses & develop in increasing gestational age but the kidney in foetuses are lobulated which is absent successively. Aborted human foetuses without obvious congenital anomaly of gestational age between 12 weeks and 36 weeks collected and processed for histological sections by H/E stain. This study was done to correlate the chronological pattern of kidney development in this geographical eastern region of India, Odisha & compare the results from other researchers nationwide & worldwide.
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