International Journal of Medical and Health Research

International Journal of Medical and Health Research

(MCI Approved Journal)

ISSN: 2454-9142

Vol. 4, Issue 5 (2018)

The association between serum zinc level and febrile seizures in childhood

Author(s): Dr. SY Ingale, Dr. Madhura Karguppikar, Dr. Raghav Kakar
Background: Febrile seizure defined by national institute of health as “an event in infancy or childhood usually occurring between 3 months to 6 years but without evidence of intracranial infection or defined cause for seizure”. Serum Zinc levels are shown to be low in febrile seizure in some studies. Hence we want to study this association in our study group.
Objective: To study the association between serum zinc levels and febrile seizures in childhood.
Method: A prospective case control study was done in Krishna Institute of Medical Sciences. All children with febrile seizure between 3 months and 6 years from Pediatric ward of Krishna institute of medical sciences, Karad, were taken as cases. Detailed clinical history comprising of age, sex, body temperature at admission, cause of fever, history of recent zinc supplementation, seizure history, duration, frequency, Type of seizure (simple or complex) was taken. Serum zinc level was measured using zinc kit by colorimetric method between cases and controls. Normal serum zinc levels is 60-120 µgm/dl.
Results: Out of 60 cases, 40 had low serum zinc levels and 20 had normal values. Out of 60 controls, 30 controls with fever, 6 had low serum zinc levels, 20 had normal values and 4 had high values. 30 controls without fever, 4 had low values and 26 had normal values.
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