Vol. 4, Issue 5 (2018)
Prevalence of nasal carriage of coagulase negative staphylococcus among medical students and its antibiotic susceptibility pattern
Author(s): Yohesh MS, Venkata Raghavendra Rao A, Reena Rajan
Abstract: Introduction: The human anterior nares are known to be the principle habitat of both commensals and opportunistic pathogens such as Staphylococcus aureus and Coagulase negative Staphylococcus. The spread of multidrug resistant coagulase negative staphylococcus is a major concern. Aims & Objectives: The present study was conducted to know the prevalence of asymptomatic nasal carriage of CONS among medical students and to determine their antibiotic susceptibility patterns Materials & Methods: A total of 154 medical students in their preclinical and clinical years were included in this study and were categorised into four groups according to the degree of hospital exposure. Nasal swab from each subject was collected using moistened sterile cotton swab and Coagulase negative staphylococci were identified by standard biochemical methods. Antibiotic susceptibility testing is done on these isolates by Kirby Bauer disk diffusion method and methicillin resistance was tested by using Cefoxitin (30 µg) disc. Results: The prevalence of CONS in our study was found to be 89.61 %. The prevalence of Methicillin resistant Coagulase Negative Staphylococcus (MRCONS) and Methicillin sensitive Coagulase Negative Staphylococcus (MSCONS) were found to be 10.87 % and 89.13% respectively. All isolates were susceptible to Linezolid, Vancomycin, Gentamicin, Teicoplanin and Clindamycin. Conclusion: Health professional should be educated and trained about the maintenance of hygiene and infection control and the effective use and misuse of antibiotics. Regular screening of carrier is essential for prevention of nosocomial infection.
Please use another browser.