Vol. 4, Issue 8 (2018)
A comparative study on lipid profile of type 2 diabetes mellitus patient with healthy subjects: A hospital based study
Author(s): Dr. Nandani, Dr. Abhay Kumar, Dr. Nipendra Kishore, Dr. Ajay Khanna
Abstract: Objectives: objective of our study was to compare the lipid profile of type 2 diabetes mellitus patients with healthy individuals. Methods: A detail history, clinical examination and relevant investigations were performed to all cases. Plasma glucose estimation was performed by using RFCL kit on the microlab -300 Semi Auto- analyzer supplied by Merck. Total cholesterol was estimated quantitatively by CHOD-PAP technique. Serum Triacylglycerol was estimated quantitatively by GPO-ESPAS technique. High density lipoproteins (HDL-C) was estimated quantitatively by PEG-PAP method. Very low density lipoproteins (VLDL-C) was estimated from serum triacylglycerol level using Friedewald formula and low density lipoproteins (LDL-C) was calculated by subtracting serum HDL and VLDL from total serum cholesterol. Results: Data was analyzed with the help of SPSS software. P value was taken ≤ 0.05 for significant differences. Conclusions: This present study was concluded that diabetic state had deleterious effects on lipid profile. All constituent of lipid profile was increased in patients with type 2 diabetes mellitus except HDL which was a negative trend with advancing age of patients with diabetes mellitus as compared non diabetes mellitus healthy subjects. Hence, as state of diabetes mellitus was increased, constituent of lipid profile were also increased except HDL.