International Journal of Medical and Health Research

International Journal of Medical and Health Research


(MCI Approved Journal)

ISSN: 2454-9142

Vol. 4, Issue 9 (2018)

Association of quality of life with disease severity in psoriasis

Author(s): Dr. Deepak Sharma, Dr. Priyanka Sharma
Abstract:
Background: Psoriasis has been shown to affect physically, socially as well as psychologically, thus affecting the day to day life of patients.
Aims and Objective: To measure quality of life and its relationship with severity of disease in psoriasis patients.
Materials and Method: Hundred and ten patients with psoriasis were studied at the Department of Dermatology, Era's Lucknow Medical College and Hospital, Lucknow for one year. Disease severity using Psoriasis Area and Severity Index (PASI) was compared with quality of life of patients which was measured using WHO-BREF Quality of life scale standardized to 100-point with lower scores indicating poor quality and higher scores indicating good quality of life. Detailed demographic and clinical profile of each patient was also recorded.
Results: Mean age of patients was 33.64+8.55 years, majority were males (62%) and urban residents (73%). Housewives (42%) were the most common occupational groups. Majority had gradual onset (59%), maximum (47%) had onset of symptoms for <1 year, 11% had pruritus, >3 sites were involved in 52% and koebernisation in 45%. A total of 46% reported of seasonal variability. Severity of disease (PASI) scores were 0-24, 25-48 and >48 in 61%, 28% and 11% cases respectively. Mean overall QOL score of study population was 59.23+ 7.28. Mean scores for physical, psychological, social and environmental domains were 16.12+1.62, 13.19+ 4.24, 7.11+1.42 and 22.61+ 6.11 respectively. Mean quality of life scores of patients with higher PASI scores (25-48 and >48) were significantly lower as compared to those for lower PASI scores (0-24) (p<0.001).
Conclusion: The findings of study showed that quality of life of patients with psoriasis was highly impaired and it was related with the severity of disease too.
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