Vol. 5, Issue 10 (2019)
Scenario of serum electrolyte, lipid and thyroid profile in Type II Diabetes Mellitus of Kashmir Valley India
Author(s): Anjum Nisa, Showkat Ahmad Bhat, Sabhiya Majid3, Quratul Ain Mushtaq, Tehseen Hassan, Akbar Masood
Abstract: Diabetes Mellitus (DM) is a metabolic disease of great concern worldwide and is a global pandemic disease characterized by chronic hyperglycemia. Apart from other factors, the underlying mechanism pertaining to the electrolyte imbalance, lipid imbalance and thyroid imbalance has to be explored. Hence the study was designed to evaluate scenario of serum biochemical parameters, electrolyte and thyroid profile in the Type II Diabetes Mellitus (T2DM) in Kashmir valley India. This study is Hospital-based case-control study and was carried out in major referral SMHS hospital in Kashmir. In our study Cases (n-100) were composed of patients with Type II Diabetes Mellitus, and controls (n-100) were healthy volunteers. The study showed a significant increase in all lipid parameters, except HDL in T2DM patients on comparison with normal controls. Thyroid dysfunction has been frequently encountered in diabetic patients with hypothyroidism being the most common type of dysfunction as in our study the levels of serum TSH was significantly increased but T3 and T4 levels were significantly decreased in cases when compared to controls, while status of electrolytes showed significantly elevated sodium (hypernatremia), mild elevation of potassium (hyperkalemia), chloride (hyperchloridemia), but decrease in Magnesium levels (Hypomagnesaemia). These aberrations could be due to the hyper tonicity of blood and redistribution of water and electrolytes noticed in DM. It may be concluded that in type II DM, assessment of electrolytes, lipid and thyroid related abnormalities are important to monitor the prognosis of type II DM patients. Hence there is need for the routine assay of these above parameters in diabetic patients so that there will be improvement in the quality of life and reduce the morbidity rate in diabetic patients.