Vol. 5, Issue 11 (2019)
Chronic kidney disease in children of paediatric emergency observation and referral unit admitted in hospital: a study in tertiary care hospital, Dhaka, Bangladesh
Author(s): AKM Khairul Islam, Manzoor Hussain, Quamrun Nahar, Sayed Shafi Ahmed, Md. Abu Tayab
Abstract: Introduction: Chronic Kidney Disease (CKD) for children is a major problem of public health both in poor and developed countries. This study aimed to investigate the diagnosis and the management options of CKD for children. Objective: To find out Chronic Kidney Disease in Children of Paediatric Emergency observation and Referral Unit admitted in Hospital. Patients and Methods: This study retrospectively evaluated patients who had Chronic Kidney Disease (CKD) in the Paediatric Emergency observation and Referral Unit in tertiary Care Hospital, Dhaka, Bangladesh between July 2018 and December 2018. Results: Over 6 month’s period, we diagnosed and managed 41 children with CKD. The estimated incidence of CKD is 4.7 new cases per million-child population per year. Parental consanguinity was found in 16 patients (39%). Family history with kidney disease was noted in 6 cases (14.6%). Malformations of the urinary tract were observed in 24 patients (58.5%). Other causes are divided into hereditary kidney disease in 8 patients (19.5%) predominated by primary hyperoxaluria, in vascular nephropathy who were objectified in 5 patients (12%) whereas glomerulopathy were represented in 3 cases (7.5%). No etiology was found in 1 patient. Over the 6 month’s 22 patients (54%) had renal replacement therapy (RRT). Peritoneal dialysis (PD) was practiced in over then 90% of patients. A passage from peritoneal dialysis to hemodialysis was done in 8 patients. Only four patients had a kidney transplant. The rate of overall mortality in our series was 40% with median of follow-up in 54 months. Conclusion: In Bangladesh and in all low source country children with CKD must be treated by pediatric nephrologists and the pediatric renal transplantation must be developed.