Vol. 5, Issue 12 (2019)
Clinical evaluation of antibiotic utilization pattern in surgical department in Vardhman institute of medical sciences
Author(s): Dr. Prem Prakash, Dr. Ashok Kumar Jha
Abstract: Antibiotics are powerful and effective drugs in the fight against infectious diseases caused by bacteria, and have saved millions of lives since their first appearance about 50 years ago. Rational use of antibiotics is extremely important as injudicious use can adversely affect the patient, cause emergence of antibiotic resistance and increase the cost. As per the World Health Organization, rational use of drugs requires that patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements for an adequate period of time, and at the lowest cost to them and their community (WHO,1987). The use of antibiotic prophylaxis has been shown to prevent post-surgical wound infection. When employed rationally, significant reduction in the mortality and morbidity and saving in resources can be achieved. Hence based on above findings the present study was planned for Clinical Evaluation of Antibiotic Utilization Pattern in Surgical Department in Vardhman Institute of Medical Sciences. The present study was planned in Department of Surgery, Vardhman Institute of Medical Sciences, Pawapuri, Nalanda, Bihar. Total 50 patients undergone the surgical procedure in the hospital were included in our study. All medically relevant information was noted in a predefined data collection form. Alternatively, these case charts were reviewed for prescription of antibiotics. The demographic data and the detailed history of patient regarding past, present, family, personal and drug history was taken. The other details like the present diagnosis, reason for the present admission, any investigations done to confirm the diagnosis were also noted. The data generated from the present study concludes that Third generation cephalosporin was the preferred or most prescribed choice of drug for prophylaxis followed by penicillins. The average number of antimicrobials prescribed in surgery department was 3 per patients. Amoxicillin and clavulanate were the fixed drug combination that was prescribed maximally.