Vol. 5, Issue 2 (2019)
Assessment of histopathological evaluation of breast lesions: neoplastic and non-neoplastic lesions in females from Bihar
Author(s): Dr. Preety Saha
Abstract: Breast neoplasms are heterogeneous. Benign breast lesions being more common than malignant tumors. The incidence of benign breast lesions begins to rise during the second decade of life, peaks in the fourth and fifth decades. Increased risk of breast cancer is associated with proliferative and atypical lesions. Diagnostic modalities such as mammography, ultrasonography, and fine-needle aspiration cytology are being increasingly used. According to Indian Council of Medical Research statistics, 10,000 breast cancers are being diagnosed every year in India and more than 70% of them are diagnosed in advanced stage. By 2020, the incidence of breast cancer in India is expected to double. Hence based on the above literature findings the present study was planned to evaluate the histopathological spectrum of neoplastic and non-neoplastic lesions of breast. The present study was planned in the Department of Pathology, Patna Medical College and Hospital, Patna from Dec 2018 to April 2019. Total 25 cases of the breast lumps refereed to our hospital were included in our study. A working diagnosis was arrived at by analysis of history and clinical examination following which the lump was received for histopathological examination as biopsy, lumpectomy or MRM specimen in 10% formalin. The standard tissue processing protocols were followed and 5m thick sections were cut and stained with hematoxylin and eosin for morphological analysis. The data generated from the present study concludes that it is also important to assess a patient’s risk of developing breast cancer so that the most appropriate treatment modality for each case can be established. Thus breast self-examination and education to females is very important in cases of benign breast tumors. Histopathological evaluation becomes necessary for such cases and plays a pivot role in their final diagnosis. It also becomes helpful to surgeons for making decision of further operative management of the patient.