Vol. 5, Issue 2 (2019)
Clinical assessment of endocrine gland neoplasms excluding thyroid in patients from Bihar region
Author(s): Dr. Preety Saha
Abstract: Tumours of endocrine glands, although rare in the context of the overall burden of oncological disease, have provided important insights into the mechanisms of sporadic and familial tumour formation, with an overt incidence of 0.6–1.5 per 100 000 per year. Other malignant endocrine tumours, including adrenocortical carcinoma, carcinoid and other neuroendocrine tumours are extremely rare, with incidence figures of less than 0.5 in 100000 per year. Hence the present study was planned to evaluate the endocrine gland neoplasms excluding thyroid. The present study was planned in the Department of Pathology, Patna Medical College and Hospital, Patna from Aug 2018 to Dec 2018. Total 50 cases of the endocrine neoplasm were enrolled in the present study. Specimens received were analysed and the occurrence of each subtypes were tabulated and its % ages were calculated and compared with other studies. Similarly, demographic variables like age and sex of the patient and the clinical presentations of these tumours were also tabulated and compared with other studies. The data generated from the present study concludes that thyroid lesions predominantly affecting females during 3rd and 4th decades of life and commonly present as neck swelling. Multinodular goiter was the commonest non-neoplastic lesion followed by colloid goiter. Follicular adenoma was the most common benign neoplasm found while papillary carcinoma was the only and most common malignant tumor. Newly classified borderline category having NIFTP, is indolent malignant tumor with excellent prognosis.