Vol. 5, Issue 2 (2019)
Assessment of antibiotic susceptibility pattern of Escherichia coli observed in urine samples of UTI Patients
Author(s): Dr. Ashok Prasad, Dr. Ajay Kumar, Dr. Pramukh Bhattacharya
Abstract: The infection of urinary tract by Escherichia coli are important and serious problems in the clinical field. Moreover the bacterial urinary tract infection is the common danger disease. Therefore, the present investigations were undertaken to study the prevalence and antibacterial susceptibilities of Escherichia coli isolated from patients with urinary tract infections. The study was planned in the Department of Microbiology and Pathology under guidance of Prof. (Dr.) Pramukh Bhattacharya in M.G.M Medical College & LSK Hospital Kishanganj. Total 50 patients were found positive were enrolled in the present study. Each sample was mixed well and aseptically inoculated with 4 mm diameter nichrome wire loop on blood agar and Mac Conkey agar plates and incubated at 37o C for 24 hours aerobically. Significant UTI was defined as the presence of >105 colony forming unit (CFU)/ml in the culture. All positive cultures were further identified by their cultural characteristics, Gram stain and battery of biochemical reaction. The data generated from the present study suggest that Escherichia coli isolates from urinary tract infections have showed resistance too many of the routine antibiotics in our study. This information may directly influence the choice of empirical antibiotic therapy for UTI. Multidrug resistant uropathogenic E. coli is an expanding public health threat.