Vol. 5, Issue 2 (2019)
A comparative on haemodynamic effect of ropivacaine vs ropivacaine plus dexmedetomidine in supraclavicular brachial plexus block: A randomized controlled double blind study in tertiary care centre
Author(s): Dr. Zameeruddin, Dr. Mohammad Imranullah Khan
Abstract: This primary aim of the study is to investigate the analgesic effect of ropivacaine in combination with dexmedetomidine versus ropivacaine alone on brachial plexus block to provide alternative anesthetic means for upper limb trauma surgery. This prospective, randomized and double-blinded study included total 60 patients of either sex with age between 18-60 years posted for various elective upper limb surgery and randomly allocated into 2 equal groups of 30 each. Control Group-R received injection ropivacaine (0.75%) 30 ml plus 1 ml normal saline and Group-RD received injection ropivacaine (0.75%) 30 ml plus dexmedetomidine 25 μg (1 ml) for supraclavicular brachial plexus block using the peripheral nerve stimulator. monitoring of vitals (systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR)), partial oxygen saturation ratio determined every 5 mins in 1st 30 mins and then every 15 mins during 1st hr followed by every 2nd hourly during 24 hrs. There was good haemodynamic stability in both groups. SBP and DBP in Group-R and Group-RD with values were comparable between the groups. The difference was statistically more significant.