Vol. 5, Issue 2 (2019)
Clinical evaluation of hypothyroid patients by estimation of uric acid
Author(s): Dr. Anand, Dr. Sharmila Dev
Abstract: Many studies were done to assess serum creatinine and uric acid levels of hypothyroid patients. But, as far we know, no such study was done in our population. So, we designed this study in our population for evaluation of uric acid levels in hypothyroid patients and that might be helpful for clinical management of hypothyroid patients with hyperuricemia. The present study was planned in the Department Of Biochemistry, Jawaharlal Nehru Medical College, Bhagalpur, Bihar. Total 50 patients diagnosed clinically and biochemically as hypothyroid were enrolled in the present study. The 25 patients were divided in Group A as Hypothyroid cases and remaining 25 patients were evaluated as a control cases. The blood collected in a plain vacutainer. Serum obtained after centrifugation was divided into two aliquots – one for thyroid profile and the other for uric acid, and were stored at -20 °C until analysis. The data generated from the present study suggests that the Uric acid levels within physiological limits are observed as elevated in hypothyroid subjects. Hypothyroidism affects renal blood flow, GFR, tubular function and also water and electrolyte balance. Therefore, patients presenting with these biochemical abnormalities are recommended to be investigated for hypothyroidism and vice a versa.