Vol. 5, Issue 2 (2019)
Evaluation of albuminuria and reduced estimated glomerular filtration rate between first-degree relatives of chronic kidney disease patients from Bihar region
Author(s): Dr. Satyam Mohan, Dr. Kunal
Abstract: The prevalence of hypertension is high in India and hypertensive nephropathy is a common cause of chronic kidney disease. Hence the present study was undertaken to evaluate the association of serum creatinine, albuminuria and eGFR among hypertensive and non-hypertensive individuals to determine the better predictor of renal impairment. Hence the present study was planned to assess the Albuminuria and reduced estimated glomerular filtration rate among first-degree relatives of patients with chronic kidney disease. The present study was planned in the Department of Nephrology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar. Total 100 individuals were enrolled in the present study. from July 2018 to Dec 2018.These were divided in to the two study groups as 50 cases of the first degree relatives of CKD patients and 50 are control cases. The inclusion criteria control group is the patients do not have family or personal history of the CKD and age above 18 years. The individuals affected by other chronic diseases and on medicine that affects the kidney functions were excluded from the present study. The present study concludes the data regarding relatives of patients with CKD found a greater prevalence of CKD, albuminuria, and reduced eGFR among the first degree relatives of patients with CKD. It can also be concluded that presence of hypertension serves as a modifiable independent risk factor for albuminuria while the presence of proteinuria and increasing age were found to predict reduced eGFR in first degree relatives. The prevalence of albuminuria increases with the duration of hypertension. Early screening of essential hypertensive patients for albuminuria and aggressive management of hypertension might reduce the burden of diseases due to renal damage secondary to hypertension in the community.