Vol. 5, Issue 3 (2019)
Incidence of hyperuricemia in patients with diabetes as compared to non-diabetic patients
Author(s): Dr. Ranjan Kumar, Dr. Jitendra Kumar, Dr. Ravi Shankar, Dr. Amit Kumar Ranjan
Abstract: Background: Diabetes mellitus is a group of disorders characterized by chronic hyperglycemia associated with disturbance of carbohydrate, fat and protein metabolism due to absolute or relative deficiency of insulin secretion or its action. Several studies performed earlier have reported that high serum uric acid level is strongly associated with prevalent health conditions such as obesity, insulin resistance, metabolic syndrome, essential hypertension and renal disease. The aim of this study is to compare the incidence of hyperuricemia in diabetic and non-diabetic patients in southern Bihar. Methods: A hospital based cross-sectional study was conducted at Narayan medical college and hospital, Sasaram, Bihar, India. A total of 445 patients of age more than 40 years were included in the study after obtaining an informed consent. The results were expressed as a percentage of the assessed population. Results: Only about 42% of the total study population was normal. 57.5% were found to have elevated serum uric acid levels. Males, Elderly, obese, non-vegetarians, pre diabetic and diabetic, showed higher serum uric acid levels. Conclusion: High prevalence of hyperuricemia was seen in diabetic patients. The uric acid levels may serve as a potential biomarker of deterioration of glucose metabolism. Further research on a larger population is required to get a wider picture about the incidence and its causes. Creating awareness, early diagnosis and treatment can help the target population.