Vol. 5, Issue 3 (2019)
Clinical evaluation of administration a single dose of antibiotic in surgical treatment of laparoscopic appendectomy
Author(s): Dr. Pranay Kumar, Dr. NP Narayan
Abstract: A single, effective and nontoxic drug is used to prevent infection by a specific microorganism or to eradicate an early infection. Single or multiple dosage regimes of antibiotics will be depending upon the patient resources, the surgical condition of the patient and the vulnerability of the patient for infection. Hence based on the literature findings the present study was planned to assess the efficacy and outcome of the single dose of antibiotics in patients undergoing the laparoscopic appendectomy. The study was planned on the 25 patients undergoing the uncomplicated laparoscopic appendectomy. The patients admitted to the Department of Surgery in Patna Medical College and Hospital, Patna from Dec 2017 to Dec 2018 Were enrolled in the present study. All the patients received one dose of preoperative intravenous antibiotics (cefazoline 1 gram and metronidazole 500 milligram) one hour before surgery. In the second group, the patients received 3 doses of antibiotics (cefazoline 500 milligram and metronidazole 500 milligram every 8 hours). Based on the data generated from the present study it can be concluded that single dose prophylactic preoperative antibiotics would be sufficient in cases of laparoscopic appendicectomy for simple uncomplicated non-perforated acute appendicitis.