Vol. 5, Issue 3 (2019)
Evaluation of the levels of the antithyroid peroxidase antibodies in females suffering from polycystic ovary syndrome (PCOS)
Author(s): Dr. Lata, Dr. Archana Sinha
Abstract: Thyroid disorders and polycystic ovary syndrome (PCOS) are two of the most common endocrine disorders in the general population. Although the etiopathogenesis of hypothyroidism and PCOS is completely different, these two entities have many features in common. Whether this is due to some common factors predisposing an individual to both disorders, or due to a pathophysiological connection between the two disorders has not been established until now. Hence the present study was planned to assess the Antithyroid Peroxidase Antibodies in females suffering from polycystic ovary syndrome. The present study was done in the Department of Obstetrics Gynaecology, Indira Gandhi Institute of Medical Science, Patna from Aug 2018 to Dec 2018. Total 50 females were included in the study. 25 patients diagnosed with the Polycystic Ovary Syndrome (PCOD) coming to outdoor of this hospital, were enrolled in the present study. 25 females in reproductive age with regular menstrual cycles, no signs of hyperandrogenism, normal ovaries on pelvic ultrasound examination and normal level of free testosterone were enrolled in control group. Various parameters like TSH, free T4, antithyroid peroxidase antibody, total testosterone were measured in the all patients. The type of assay used was chemiluminescent immunoassay (CLIA). There is enough literature support to argue that prevalence of subclinical hypothyroidism/thyroid autoimmunity is increased in women with PCOS patients. Thyroid disorders in the course of PCOS, are observed significantly more frequently than in the general population. However, their concomitance in the context of fertility disorders has not been investigated extensively.