Vol. 5, Issue 3 (2019)
Gestational age, prematurity and birth asphyxia on platelet indices in neonates
Author(s): Dr. Amresh Kumar Jha, Dr. AK Jaiswal
Abstract: Platelets in newborn demonstrate several activities, including hemostasis and maintaining integrity of blood vessels. Hemostasis of a neonate is a dynamic system that gradually evolves throughout gestation and early infancy. The newborn physiological status affects the risk for and the presence of acquired hemostatic disorders. Prematurity, birth asphyxia (BA) and small for gestational age (SGA) babies have been associated with hemostatic abnormalities. The present study was planned to evaluate the effect of gestational age, prematurity and birth asphyxia on platelet indices in neonates. The present study was planned in the Upgraded Department of Paediatrics (Neonatology) in Patna Medical College and Hospital, Patna from June 2018 to Dec 2018. Total 100 neonates were enrolled in the present study and divided in four study groups of controls, Small Gestational Age (SGA), preterm and Birth Asphyxia (BA). Platelet indices may represent easy and early biomarker for identification of thromboembolic status in neonates, and thus improves the neonatal outcome. Platelet count & plateletcrit was decreased, mean platelet volume & platelet distribution width was significantly increased in SGA and premature newborns due to platelet activation.