Vol. 5, Issue 5 (2019)
Anti-thrombotic effects of Camellia sinensis (Tea): A systematic review
Author(s): Kipyegon Shadrack, Alkizim Faraj, Kigundu Alex, Ngure Kenneth, Karuguti Wallace
Abstract: Tea, a product of Camellia sinensis is the second most consumed drink globally after water. It has so many documented medicinal uses including but not limited to anti-inflammatory, anti-oxidative, anti-carcinogenic and cardiovascular effects. Studies have also reported it to have antithrombotic activity. Thrombosis which refers to intravascular coagulation is implicated in the development of many cardiovascular disorders like ischemic heart disease. Prevention of these diseases can be achieved by use of antithrombotic drugs like aspirin and clopidogrel. This study reviews the antithrombotic effects of Camellia sinensis. Five databases were searched for articles to review. Those articles whose titles were pre-qualified were subjected to the Population, Intervention, Comparison and Outcome (PICO) screening hence further qualifying 19 articles. 10 articles were left out during retrieval of full text articles and the 9 obtained and subjected to methodological appraisal which resulted to qualification of 5 experimental studies. Each of these studies reported at least one antithrombotic effect with 2 sets registering similar results. Anti-platelet and anticoagulant effects are examples of antithrombotic effects reported in these studies. Since this review has shown that Camellia sinensis has antithrombotic properties, suggestion can be made that regular consumption of tea reduces risk of developing ischemic heart diseases.
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