Vol. 5, Issue 5 (2019)
Clinical evaluation of septicemia patients identified with candida species in Bihar population
Author(s): Dr. Ahsan Hamidi, Dr. Shamim Ahmad, Dr. Shiv Nandan Singh
Abstract: Infections leading to sepsis are usually bacterial, but may be fungal or viral. Gram-positive bacteria was the predominant cause of sepsis before the introduction of antibiotics. Over the past year, we noticed an increase in the isolation rate of nonalbicans Candida species from cases of neonatal septicemia, which prompted us to undertake the present study; to analyse and evaluate the change in the species distribution of Candida species in neonatal septicemia and determine their in vitro antifungal susceptibility and the risk factors associated with their acquisition. The data from the 125 cases were collected and presented as below. Infection with unusual organisms is an increasing problem. Due to advances in medical and surgical management, an increase in nosocomial fungal infection rate has been observed. Candidemia is an emerging problem in healthcare settings. Knowledge of the epidemiology of candidemia can help to salvage patients, who are in the productive age group, with few with underlying medical condition. The changing epidemiology of candidemia highlights the need for close monitoring of Candida species distribution and susceptibility to optimize treatment and outcome. It is apparent from the results of the present study that routine identification of Candida isolates to the species level, and the detection of resistant strains by antifungal susceptibility test is essential. Furthermore, there is a continued need for surveillance of candidemia to monitor changes in the epidemiological features and antifungal susceptibility and also to develop and evaluate prevention strategies.