Evaluation of factors responsible for the neonatal sepsis in Darbhanga, Bihar
Dr. Krishan Kumar Jha, Dr. Nagendra Prasad Gupta
Systemic infection in the newborn is the commonest cause of neonatal mortality. Data from National Neonatal Perinatal Database 2000 suggests that Klebsiella pneumoniae and Staphylococcus aureus are the commonest causes of neonatal sepsis in India. Two forms of clinical presentations have been identified. Early onset sepsis, probably related to perinatal risk factors, usually presents with respiratory distress and pneumonia within 72 hours of age. Late onset sepsis, related to hospital acquired infections, usually presents with septicemia and pneumonia after 72 hours of age. Hence the present study was planned to evaluate the factors responsible for the neonatal sepsis in the darbhanga, bihar region. The present study was planned in the Department of Paediatrics, Darbhanga Medical College and Hospital. Out of the Total 350 neonates admitted to the Hospital 30 cases were found positive for the septicemia were enrolled in the present study. Case records of newborns admitted to the Neonatal Intensive Care Unit of our tertiary care hospital during this period were obtained from the medical records section. Details of newborns with the final diagnosis of sepsis were reviewed. Neonates fulfilling the criteria for community- and hospital-acquired infections with positive blood culture were included in the study. The study also emphasizes the need for preventive measures such as early and exclusive breastfeeding, promoting hospital deliveries to reduce the number of community-acquired infections. The present study showed an alarming increase in the prevalence of strains resistant to the commonly used antibiotics. Therefore, a great caution is required in the selection of suitable antibiotic therapy. Early diagnosis with a reasonable degree of accuracy will help the clinician to decide on the usage of proper antibiotic which will help in reducing the morbidity and mortality.