Evaluation of different parameter of pulmonary function test in patients suffered from diabetes mellitus
Dr. Arohi Kumar
Type 2 diabetes mellitus is a heterogeneous group of disorder characterized by variable degrees of insulin resistance, impaired insulin secretion, and increased glucose production. There is an alarming increase in the incidence and prevalence of diabetes mellitus particularly in Asian Indians. The major morbidities in type 2 diabetes mellitus are due to its microangiopathic and macroangiopathic complications, which affect eyes, kidneys, nerves, heart, and major vessels. The development of these complications may be related to biochemical alterations in connective tissue constituents, particularly collagen and elastin as well as macroangiopathy due to a non-enzymatic glycosylation of proteins induced by chronic hyperglycemia. The presence of an extensive pulmonary microvascular circulation and abundant connective tissue raises the possibility that lung may also be a target organ in diabetes. The present study is undertaken to study pulmonary function tests in patients having diabetes mellitus. The present study was planned in Narayan Medical College and Hospital, Jamuhar Sasaram, Bihar. The Pulmonary function test was assessed in the diabetes cases. Total 50 cases were enrolled in the present study. The total patients were divided into the two study groups. The 25 cases were evaluated in Group A as diabetic patients and 25 cases were evaluated in the Group B as control patients. After demonstrating the technique for carrying out pulmonary function tests, subjects were made to undergo pulmonary function tests, using medspiror, for 3 times at every 15 minutes interval and best of 3 was taken into account. The data generated from the present study concludes that diabetic patients showed impaired lung function. This reduced lung function is likely to be a chronic complication of diabetes mellitus. Lung functions need to be checked periodically to assess the severity of impairment. However, a need of larger prospective study with long observational course to confirm these observations is required. It is therefore important to increase awareness of potential damage to the lungs in our patients with diabetes and encourage ideal BMI for this group of persons. DM being a systemic disease, also affects lungs causing restrictive type of ventilatory changes probably because of glycosylation of connective tissues, reduced pulmonary elastic recoil, and inflammatory changes in lungs.