International Journal of Medical and Health Research

International Journal of Medical and Health Research


International Journal of Medical and Health Research
International Journal of Medical and Health Research
Vol. 5, Issue 9 (2019)

Plasma fibrinogen levels in type 2 diabetes mellitus: A case control study


Dr. Shivangi, Dr. Dhanveer Singh, Dr. Abhishek Gupta

Aim: The aim of the present study was to know the plasma fibrinogen levels in the patients of type 2 diabetes mellitus patients. Material and method: The present study was conducted in the department of Medicine at Chattrapati Shivaji Subharti Hospital from February 2017 to January 2019. This study involved a total of 100 patients of which 50 were taken as cases (diabetics) and the other 50 as controls (non-diabetics) according to the inclusion and exclusion criteria. The various parameters that were studied included age of the patient (years), sex, body mass index (kg/m2), smoking, blood pressure (mm Hg), plasma fibrinogen level (mg/dl), glycosylated hemoglobin (%), microalbuminuria, total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride level. Data were tabulated and examined using the Statistical Package for Social Sciences Version 22.0 Results: Mean HbA1c (%) level was found to be 7.89±1.40 in the case group while the same was reported to be 4.2±1.73 in the control group with statistically significant difference. Mean microalbuminuria level was found to be 436.8±94.32 in the case group while the same was reported to be 316.81±80.31 in the control group. Mean fibrinogen level in case and control group was 396.63±104.89 and 252.70±72.38 respectively. Conclusion: In this study, the type 2 diabetic patients were found to have significantly higher levels of fibrinogen in comparison to non-diabetic subjects. This study shows that these newer risk factors like age, blood pressure, BMI, and blood glucose can be measured in diabetic patients for a better risk prediction.
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