Plasma fibrinogen levels in type 2 diabetes mellitus: A case control study
Dr. Shivangi, Dr. Dhanveer Singh, Dr. Abhishek Gupta
Aim: The aim of the present study was to know the plasma fibrinogen levels in the patients of type 2 diabetes mellitus patients. Material and method: The present study was conducted in the department of Medicine at Chattrapati Shivaji Subharti Hospital from February 2017 to January 2019. This study involved a total of 100 patients of which 50 were taken as cases (diabetics) and the other 50 as controls (non-diabetics) according to the inclusion and exclusion criteria. The various parameters that were studied included age of the patient (years), sex, body mass index (kg/m2), smoking, blood pressure (mm Hg), plasma fibrinogen level (mg/dl), glycosylated hemoglobin (%), microalbuminuria, total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride level. Data were tabulated and examined using the Statistical Package for Social Sciences Version 22.0 Results: Mean HbA1c (%) level was found to be 7.89±1.40 in the case group while the same was reported to be 4.2±1.73 in the control group with statistically significant difference. Mean microalbuminuria level was found to be 436.8±94.32 in the case group while the same was reported to be 316.81±80.31 in the control group. Mean fibrinogen level in case and control group was 396.63±104.89 and 252.70±72.38 respectively. Conclusion: In this study, the type 2 diabetic patients were found to have significantly higher levels of fibrinogen in comparison to non-diabetic subjects. This study shows that these newer risk factors like age, blood pressure, BMI, and blood glucose can be measured in diabetic patients for a better risk prediction.