The study of association of hypothyroidism and sleep disordered breathing in symptomatic adult Patients
Dr. Rishi Yadav, Dr. Eema Chaudhary
Aim: was to evaluate the prevalence of symptoms of sleep apnoea and related breathing disorders in patients suffering from hypothyroidism on the basis of Epworth sleepiness scale. Material and method: The present hospital based cross sectional study was conducted among 90 patients reporting to the department of respiratory medicine and department of general medicine at Chattarpati Shivaji Hospital of Subharti Medical College, Meerut. Clinical history, BMI, blood pressure (recorded after at least 5 minutes of rest in both arms sitting/supine position) was recorded. Blood samples of 5 ml drawn after 12 hours (overnight fasting) for the measurement of thyroid profile and fasting plasma glucose. OSA is defined as apnoea-hypopnoea index (AHI) > 5 that is more than five episodes per hour of cessation of breathing for at least 10 seconds. Results: Mean fT3 (pmol/L), fT4 (pmol/L) and TSH (mIU/mL) was found to be 1.94, 4.20 and 42.27 respectively. AHI score >5 was reported among 47 subjects. 51.06% of the subjects were having severe apnoea while moderate and mild sleep apnoea was found among 23.40% and 25.53% of the subjects respectively. Conclusion: The results of the present study concluded that patients with hypothyroidism should be assessed and evaluated for OSAS as it helps in an appropriate treatment with CPAP or thyroid supplements or both. Routine screening for thyroid disorders may prevent misdiagnosis and allows physicians to find primary condition and start hormone replacement therapy, inhibiting the progression of the primary disorder.