Study of prevalence of leukemia in pediatric age group
Dr. Shahnawaz Hasnain Warsi, Dr. Kripa Nath Mishra
Cancer is the third major killer disease in India among children after infection and malnutrition. Leukemia is the most common type of childhood malignancy. During the period of suffering, the child encounters various complications and also sustains several side-effects as unavoidable consequences of the compact treatment. Current therapy for leukemia consists of chemotherapy and radiotherapy or a combination of both and sometimes surgery. The maximum number of malignancies was noticed amongst children aged between 1-4 years. The male and female ratio was 2:1. 36% of all malignant lesions in children are leukemia. The incidence of leukemia is higher in <15 years of aged children. Leukemia is the most common childhood cancer in India. 60-85% of all leukemia reported is Acute Lymphoblastic Leukemia (ALL). Hence based on above findings the present was planned for study of Prevalence of Leukemia in Pediatric Age Group. The Present study was planned in Department of Pediatrics, Darbhanga Medical College & Hospital, Laheriasarai, Bihar. The 25 cases of the Leukaemia referred to our hospital were enrolled in the present study. Patients of ALL were treated according to BFM 90 protocol after risk stratification. High risk protocol was given only if good follow up was possible and parents were willing. AML excluding APML was treated with 7+3 regimen and CML was treated with Arsenic or imatinib mesylate. Regular examinations were done during hospital stay & any complications were recorded & treated. Study outcome was noted as discharge or death. The data generated from the present study concludes that Fever was the most common symptom while Hepatomegaly was most common sign found in Leukemia patients. Most common type of Leukemia was ALL in pediatric age group. Thrombocytopenia was most common complication found in Leukemia patients.