Clinical evaluation of levels of vitamin d in infants suffered from recurring wheezing from Bihar region
Dr. Ved Prakash Gupta, Dr. Binit Singh
Being a tropical country, vitamin D deficiency was thought of uncommon in India, however, contrary to this belief recent studies have shown its prevalence to be as high as 50-90%. Previous studies from India used older definitions (<30 ng/mL) for defining vitamin D deficiency and insufficiency hence overestimated the association between vitamin D insufficiency/deficiency and wheeze. Recent Indian as well as international guidelines redefined the vitamin D deficiency as well as insufficiency as advocate using the same for ensuring uniformity. It was observed that lot of children visiting to emergency with recurrent wheeze did not have any underlying etiology except low vitamin D levels, on the other hand many children with even florid rickets doesn’t have wheeze. Hence based on above findings the present study was planned for Clinical Evaluation of Levels of Vitamin D in Infants Suffered from Recurring Wheezing from Bihar Region. The present study was planned in Department of Paediatrics, Darbhanga medical College and Hospital, Darbhanga, Bihar, India. The study was conducted from March 2019 to August 2019. The 30 infants of age up to 24 months were enrolled in the present study. The 15 cases were enrolled in Group A as study group having wheezing and remaining 15 cases were enrolled in Group B as control group patients. Two different cut off levels were used in the study to categorize 25(OH) D concentrations. The levels above 30 ng/ml (75 mmol/L) were accepted as sufficient, the levels under< 20 ng/ml (50 nmol/L) as vitamin D deficiency and under < 10 ng/ml as extreme deficient (25nmol/L). The data generated from the present study concluded that no correlation between vitamin D levels and recurring puffed in infants was found but this may be due to the few numbers of patients that we studied with. The current findings not express important relationship among vitamin D level and recurring wheezing in the infants.